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Abstract #2743

Correlation Mapping Technique for Characterizing Pulsatile Cerebrospinal Fluid (CSF) Motion Obtained by Four Dimensional Velocity Mapping

Satoshi Yatsushiro 1 , Akihiro Hirayama 2 , Naokazu Hayashi 2 , Mitsunori Matsumae 2 , Nao Kajihara 3 , Afnizanfizal Abdullah 4 , and Kagayaki Kuroda 1

1 Course of Information Science and Engineering, Tokai University, Hiratsuka, Kanagawa, Japan, 2 Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan, 3 Department of Radiology, Tokai University Hospital, Isehara, Knagawa, Japan, 4 Faculty of Computer Science and Information Systems, Universiti Teknologi Malaysia, Johor, Malaysia

A novel technique called correlation mapping technique was proposed to characterize pulsatile cerebrospinal fluid (CSF) motion obtained by four dimensional velocity mapping. This technique comprise two functionalities, delay time mapping, which reflects the delay time in the velocity wave propagation, and maximum correlation mapping, which exhibits the similarity of the velocity wave shape. Application of this technique to 5 healthy and 5 normal pressure hydrocephalus (NPH) subjects demonstrated that the percentiles of the area with high correlation coefficients (> 0.7) in the CSF space was significantly (p < 0.05) larger in the normal group.

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