Meeting Banner
Abstract #2790

Investigation of NODDI estimates at two different magnetic fields along the rat corpus callosum

Nicolas Kunz 1 , Stphane Sizonenko 2 , Petra Susan Hppi 2 , Rolf Gruetter 1,3 , and Yohan van de Looij 4

1 CIBM-AIT, EPFL, Lausanne, Vaud, Switzerland, 2 Division of Child Growth and Development, University of Geneva, Geneva, Switzerland, 3 Department of Radiology, University of Geneva and Lausanne, Lausanne, Switzerland, 4 University of Geneva, Division of Child Growth and Development, Geneva, Switzerland

It has been shown that magnetic field strength and diffusion time (t diff ) has an influence on diffusion tensor imaging derived parameters, limiting multicentre comparisons with different MR systems. The aim of this work was to investigate effect of B0 and t diff on NODDI estimated microstructural parameters to better understand this field dependency. We demonstrate the feasibility of reconstructing NODDI model in the rodent brain in-vivo at ultra-high magnetic field using multi-b-value shells acquisition. These preliminary results suggest that FA changes along the CC are not only due to differences in axonal diameter but also to axonal orientation dispersion differences as depicted by NODDI results.

This abstract and the presentation materials are available to members only; a login is required.

Join Here