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Abstract #2794

Differential Diffusion Imaging (DDI): A novel scheme for resolving small axon diameters by a set of single PGSE experiments.

Yogesh Rathi 1 , Samo Lasic 2 , Tim Dyrby 3 , and Carl-Fredrik Westin 4

1 Harvard Medical School, Boston, MA, United States, 2 Colloidal Resource, Sweden, 3 Danish Research Centre for Magnetic Resonance, Denmark, 4 Harvard Medical School, MA, United States

We propose a novel diffusion imaging scheme called Differential Diffusion Imaging (DDI), which uses a differential of two or more standard single PGSE sequences to boost the sensitivity to restricted diffusion by isolating high frequency components of the spectrum of restricted diffusion. The DDI scheme might potentially allow resolving smaller axon diameters compared to the standard single PGSE sequences.

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