Differential Diffusion Imaging (DDI): A novel scheme for resolving small axon diameters by a set of single PGSE experiments.
Yogesh Rathi 1 , Samo Lasic 2 , Tim Dyrby 3 , and Carl-Fredrik Westin 4
Harvard Medical School, Boston, MA, United
Research Centre for Magnetic Resonance, Denmark,
Medical School, MA, United States
We propose a novel diffusion imaging scheme called
Differential Diffusion Imaging (DDI), which uses a
differential of two or more standard single PGSE
sequences to boost the sensitivity to restricted
diffusion by isolating high frequency components of the
spectrum of restricted diffusion. The DDI scheme might
potentially allow resolving smaller axon diameters
compared to the standard single PGSE sequences.
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