Abstract #2820
Diffusion reconstruction by combining Spherical Harmonics and Generalized Q-Sampling Imaging
Sudhir K Pathak 1 , Catherine Fissell 2 , Deepa Krishnaswamy 1 , Sowmya Aggarwal 1 , Rebecca Hachey 2 , and Walter Schneider 2
1
Bioengineering, University Of Pittsburgh,
Pittsburgh, PA, United States,
2
Psychology,
University Of Pittsburgh, Pittsburgh, PA, United States
There are different diffusion reconstruction algorithms
reported in the literature that can be used to assess
the micro-structure of white matter tissue in the human
brain. Most notably, constrained spherical deconvolution
(CSD) is used for single shell (constant b-value) image
acquisitions and Generalized Q-sampling imaging (GQI) is
used for Diffusion Spectrum Imaging and Multi-shell
image acquisitions. A new reconstruction method is
proposed that combines CSD and GQI to estimate the
spherical harmonics coefficients directly from the
diffusion signal. The proposed method produce improved
estimates of fiber directions and sharper ODF using CSD
and better tractography.
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