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Abstract #2837

Cortical profile of mean kurtosis and fractional anisotropy with high resolution DKI and DTI of macaque brains

Austin Ouyang 1 , Mihovil Pletikos 2 , Nenad Sestan 2 , and Hao Huang 1

1 Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, United States, 2 Department of Neurobiology, Yale University, CT, United States

The primate cerebral cortex is characterized with complicated cytoarchitecture including neurons, glial cells, dendrites and small axons. Diffusion kurtosis imaging (DKI) has the potential to delineate the cortical microstructural complexity and provide complementary microstructural information to diffusion tensor imaging (DTI). Integrating cortical MK and FA map from high resolution DKI and DTI could offer a refreshing insight into the cellular microstructure noninvasively across the cerebral cortex. In this study, we aimed to reveal the MK and FA profile across different cortical areas and explore the relationship of cortical MK and FA with high resolution DKI and DTI of macaque brains.

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