Histogram analysis of apparent diffusion coefficient maps reveals differences among the different types of uterine fibroids based on T2WIs

The aim of the study is to investigate the variation among the different T2WI types uterine fibroids by analysis of ADC histogram. Eighty patients divided in type1 of 34 patients, type2 of 36 patients, type3 of 10 patients, respectively. Conventional MRI and DWI were performed. Then, ADCq, kurtosis and skewness were derived from ADC histogram. The results showed that values of ADCq and kurtosis were significant difference between type 1 and type2type1 and type3. The kurtosis among three type are contrary to ADCq, which of type1 is lowest than others. However, there is no significant difference between type2 and type3 in ADCq, kurtosis and skewness. Therefore, ADCq and kurtosis can provide quantitative information to identify different fibroid types, which could be used as useful screening tools to guide the patients selection for MRgHIFU ablation.

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