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Abstract #2877

Investigation of the Presence and Repeatability of Intravoxel Incoherent Motion (IVIM) in Breast Parenchyma of Healthy Volunteers using an Optimised b-value Scheme

Nina L. Purvis 1 , Peter Gibbs 2 , Martin D. Pickles 2 , and Lindsay W. Turnbull 2

1 Centre for MR Investigations, Hull York Medical School, Hull, East Yorkshire, United Kingdom, 2 Centre for MR Investigations, University of Hull at HYMS, Hull, East Yorkshire, United Kingdom

A study to investigate the presence and repeatability of IVIM in breast parenchyma of healthy volunteers. Two optimised IVIM protocols were applied in 11 healthy volunteers, and the data was fitted mono- and bi-exponentially with a cut-off for D of 200s/mm2. RMSEs indicated that the biexponential fit was better. The repeatability of D for b-values10 and b-values20 was 9% and 20% respectively, with the repeatability of f and D* showing more variation at up to 0.12 and 0.039s/mm2. The results indicated that there was an IVIM effect in breast parenchyma.

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