Diffusion-Weighted Matched-phase Adiabatic Spin Echo (DW-MASE) Sequence for Ultrahigh Field Brain Diffusion-Weighted Imaging

We present a novel Diffusion-Weighted Matched-phase Spin Echo acquisition (DW-MASE) that uses semi-adiabatic radiofrequency pulses to provide increased robustness to B1 field inhomogeneity for ultrahigh field brain diffusion-weighted imaging. We show that DW-MASE leads to increased signal in regions suffering from inhomogeneous B1 when compared to conventional single-refocused diffusion. The impact of improved data quality on diffusion metrics is shown in a high resolution white matter tractography example acquired in a healthy volunteer.

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