Abstract #2895

Optimisation of single-shell HARDI for neonatal imaging

Jacques-Donald Tournier ¹ , Emer Hughes ¹ , Nora Tusor ¹ , A. David Edwards ¹ , and Joseph V Hajnal ¹

¹ Centre for the Developing Brain, Kings College London, London, London, United Kingdom

High angular resolution diffusion imaging (HARDI) sequences are now starting to be used for neonatal investigations. However, the neonatal brain is very different from the adult brain, and sequence parameters should be optimised specifically for use in this cohort. A recent study used a data-driven approach to optimise HARDI parameters for use in the adult brain, based on the angular frequency content of the DW signal. In this study, we use this approach to investigate the optimal imaging parameters for use in neonates.

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