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Abstract #2928

Modelling multiple flip angle diffusion weighted SSFP data

Saad Jbabdi 1 , Sean Foxley 1 , and Karla L Miller 1

1 FMRIB Centre, University of Oxford, Oxford, Oxfordshire, United Kingdom

Diffusion imaging with SSFP offers great temporal CNR, and is particularly suited for post-mortem whole brain imaging. We have previously shown that using multiple flip angles helps improve CNR homogeneity across the brain. Here, we use a combination of analytic and Monte Carlo simulations, coupled with real post-mortem human brain data, to demonstrate how we can model multiple flip angle DW-SSFP with a simple Gamma distribution of ADCs.

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