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Abstract #2957

Strategies for Increasing Spatial Coverage of Balanced Steady-State Free Precession Arterial Spin Labeling

Paul Kyu Han 1 , Jong Chul Ye 1 , Eung Yeop Kim 2 , Seung Hong Choi 3 , and Sung-Hong Park 1

1 Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, 2 Department of Radiology, Gachon University Gil Medical Center, Incheon, Korea, 3 Department of Radiology, Seoul National University College of Medicine, Seoul, Korea

In this study, we tested feasibility of segmented 3D approach and also optimized compresses sensing (CS) algorithms, to increase spatial coverage of pCASL-bSSFP. The segmented 3D approach efficiently increased spatial coverage of pCASL-bSSFP with no penalty in scan time and SNR. The pCASL-bSSFP-CS approach also showed good results with down-sampling factor of 4 that was converted to increased spatial coverage while no change in temporal resolution. Segmented 3D pCASL-bSSFP can be a good solution for high-resolution whole brain perfusion mapping and pCASL-bSSFP-CS may be useful for perfusion mapping with limited scan time and/or high temporal resolution such as fMRI.

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