Strategies for Increasing Spatial Coverage of Balanced Steady-State Free Precession Arterial Spin Labeling
Paul Kyu Han 1 , Jong Chul Ye 1 , Eung Yeop Kim 2 , Seung Hong Choi 3 , and Sung-Hong Park 1
Department of Bio and Brain Engineering,
Korea Advanced Institute of Science and Technology,
of Radiology, Gachon University Gil Medical Center,
of Radiology, Seoul National University College of
Medicine, Seoul, Korea
In this study, we tested feasibility of segmented 3D
approach and also optimized compresses sensing (CS)
algorithms, to increase spatial coverage of pCASL-bSSFP.
The segmented 3D approach efficiently increased spatial
coverage of pCASL-bSSFP with no penalty in scan time and
SNR. The pCASL-bSSFP-CS approach also showed good
results with down-sampling factor of 4 that was
converted to increased spatial coverage while no change
in temporal resolution. Segmented 3D pCASL-bSSFP can be
a good solution for high-resolution whole brain
perfusion mapping and pCASL-bSSFP-CS may be useful for
perfusion mapping with limited scan time and/or high
temporal resolution such as fMRI.
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