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Abstract #2959

Model-independent arterial transit time mapping using pseudo-continuous ASL

Toralf Mildner 1 , Kathrin Lorenz 1,2 , and Harald E. Mller 1

1 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany, 2 Faculty of Physics and Earth Sciences, University of Leipzig, Saxony, Germany

Mapping of Arterial Transit time by Intravascular Signal SElection (MATISSE) was introduced to obtain arterial transit times directly from temporal shifts of ASL time series acquired with short TR intervals. The RF power applied to a neck labeling coil was modulated for successive repetitions. The current work adopts this strategy to single-coil pseudo-continuous ASL by modulating the RF phase offset accordingly and, thereby, creating a smooth transition between zero and maximum labeling efficiency. Model-independent evaluation of the resulting ASL time series yielded arterial transit time maps that show reasonable patterns of human vascular territories including their border zones.

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