Moving away from single-shell?: a study on angular accuracy of constrained spherical deconvolution.
Michael Paquette 1 , Chantal M.W. Tax 2 , Alexander Leemans 2 , and Maxime Descoteaux 1
Sherbrooke Connectivity Imaging Lab (SCIL),
Universit de Sherbrooke, Sherbrooke, Quebec, Canada,
Medical Center Utrecht, Image Sciences Institute,
Diffusion MRI is commonly used to perform tractography,
in which the local reconstruction algorithms prioritize
the angular accuracy of the diffusion directions,
describing the underlying white matter bundles. This is
why single-shell HARDI is generally the acquisition
scheme of choice. One downside of single-shell
acquisitions is their inability to be applied in
high-order models that need some information about the
radial diffusion such as MAP, kurtosis or
multi-compartment models which provide interesting
microstructural diffusion features. But can we get
satisfactory orientation reconstructions from multiple
b-values diffusion data without increasing the total
number of measurements?
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