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Abstract #3037

Moving away from single-shell?: a study on angular accuracy of constrained spherical deconvolution.

Michael Paquette 1 , Chantal M.W. Tax 2 , Alexander Leemans 2 , and Maxime Descoteaux 1

1 Sherbrooke Connectivity Imaging Lab (SCIL), Universit de Sherbrooke, Sherbrooke, Quebec, Canada, 2 University Medical Center Utrecht, Image Sciences Institute, Utrecht, Netherlands

Diffusion MRI is commonly used to perform tractography, in which the local reconstruction algorithms prioritize the angular accuracy of the diffusion directions, describing the underlying white matter bundles. This is why single-shell HARDI is generally the acquisition scheme of choice. One downside of single-shell acquisitions is their inability to be applied in high-order models that need some information about the radial diffusion such as MAP, kurtosis or multi-compartment models which provide interesting microstructural diffusion features. But can we get satisfactory orientation reconstructions from multiple b-values diffusion data without increasing the total number of measurements?

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