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Abstract #3069

'Whole-Body PET/MR Imaging: Quantitative Evaluation of a Novel Model-based MR Attenuation Correction Method Including Bone

Daniel H Paulus 1 , Harald H Quick 1,2 , Matthias Fenchel 3 , Christian Geppert 3 , David Faul 4 , Yiqiang Zhan 5 , Fernando E Boada 6,7 , Kent L Friedman 6 , and Thomas Koesters 6,7

1 Institute of Medical Physics, University of Erlangen-Nrnberg, Erlangen, Germany, 2 High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 3 Siemens AG Healthcare, Erlangen, Germany, 4 Siemens AG Healthcare, New York, NY, United States, 5 Siemens AG Healthcare, Malvern, PN, United States, 6 NYU Langone Medical Center, Center for Biomedical Imaging, Department of Radiology, New York, NY, United States, 7 NYU Langone Medical Center, Center for Advanced Imaging Innovation and Research, CAI2R, New York, NY, United States

In whole-body hybrid PET/MR imaging, bone is currently disregarded in attenuation correction. For head imaging, several approaches have been proposed to consider bone, but yet, not assigned to whole-body imaging. A novel attenuation correction approach for hybrid PET/MR imaging is presented and evaluated on 19 patients that combines the routine Dixon-based soft tissue segmentation with model-based bone estimation for whole-body imaging. As a standard of reference, CT images of each patient were non-rigidly registered to the MR images. It is shown that the new method significantly improves the PET quantification in bony tissue, bone lesions, and tissue close to bone.

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