Whole-Body PET-MR Including DWI, T2w, and Gadofosveset-enhanced T1w Sequences: Evaluation of MR Performance Compared to PET-CT and Relative Benefits Provided by Each Sequence

Diffusion-weighted (DW), T2-weighted, and gadofosveset-enhanced T1-weighted images from 14 whole body PET-MR exams were assessed by 2 radiologists for presence of malignant disease as well as lesion conspicuity and delineation. Compared to PET-CT, MR showed good sensitivity and specificity on a per-organ basis but only fair specificity on a per-patient basis due to false positive findings in osseous structures. Lesion conspicuity was rated best on DW images, particularly in osseous structures. The relatively lower conspicuity on post-contrast images could have been in part due to suboptimal lesion enhancement with gadofosveset.

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