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Abstract #3127

High acceleration ability of a homemade 8-ch mouse phased array suggests the possibility for EPI-based functional studies of mice models using a standard 3T human scanner

Hui Han 1 , John Stager 1 , Wei Cao 2 , Miguel Navarro 3 , Fraser Robb 3 , Junghun Cho 1 , Nozomi Nishimura 4 , Chris Schaffer 4 , Valerie Reyna 1 , Yi Wang 1 , and Wen-Ming Luh 1

1 Cornell MRI Facility, Cornell University, Ithaca, New York, United States, 2 Tongji Hospital, Huazhong University of Science and Technology, Hubei, China, 3 GE Healthcare, Ohio, United States, 4 Biomedical Engineering, Cornell University, Ithaca, New York, United States

Here we show a homemade 8-ch mouse phased array interfaced to a standard 3T human scanner. A fact one may easily neglect is that the small imaging space allows for an excellent parallel imaging ability even for a low coil-element count (8) being used, which is a different scenario for a human coil with a larger imaging space. An initial trial, using single-shot gradient echo EPI with parameters tailored to fMRI, shows the possibility for functional studies of mice models. To our best knowledge, this is one of few first demonstrations to attempt fMRI of mice on a clinical system.

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