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Abstract #3130

Array coil and sample preparation and support system for whole brain ex vivo imaging at 100 μm

Azma Mareyam 1 , Jonathan R Polimeni 1,2 , Allison Stevens 1 , Andre Van Der Kouwe 1,2 , Loren D Bridgers 3 , Jason P Stockmann 1,2 , Matthew D Tisdall 1,2 , Lee Tirrell 1 , Allison L Moreau 1 , Ani Varjabedian 1 , Brian L Edlow 1,2 , Bruce Fischl 1,4 , and Lawrence L Wald 1,2

1 A.A. Martinos Center of Biomedical Engineering, Department of Radiology, Charlestown, MA, United States, 2 Harvard Medical School, Boston, MA, United States, 3 Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States, 4 CSAIL, Massachusetts Institute of Technology, Cambridge, MA, United States

We present an integrated system for 7T ex vivo imaging that meets several of the challenging design requirements needed to image a whole ex vivo brain at 100um isotropic resolution in 25 hours of averaging time. It incorporates a 31 channel receive array, an improved mechanical design, preamps mounted at the coil detectors, and an extended transmit coil design capable of producing high-power pulses. This new design substantially increases the range of ex vivo imaging applications.

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