Abstract #3140
Simultaneous in vivo 1 H/ 23 Na-imaging of superficial lymph nodes using 7 Tesla-MRI
Martin T. Freitag 1 , Nadia Benkhedah 2 , Pedram Yazdanbakhsh 3 , Titus Lanz 3 , Moritz Berger 2 , Mathies Breithaupt 2 , Jessica Hassel 4 , Heinz-Peter Schlemmer 1 , Mark E Ladd 2 , and Armin M. Nagel 2
1
Department of Radiology, German Cancer
Research Center, Heidelberg, Baden-Wuerttemberg,
Germany,
2
Medical
Physics in Radiology, German Cancer Research Center,
Heidelberg, Baden-Wuerttemberg, Germany,
3
Rapid
Biomedical, Rimpar, Bayern, Germany,
4
Department
of Dermatology, National Center for Tumor Diseases,
Heidelberg, Baden-Wuerttemberg, Germany
There is substantial interest to develop diagnostic
procedures for lymph node (LN) staging that feature a
high spatial resolution combined with functional imaging
techniques because conventional tomographic methods are
limited to correctly assess the nodal involvement.
23Na-imaging could be a novel approach for the
characterization of often hypervascularized lymph node
metastases because sodium is accumulated in malignant
cells and blood vessels. By using a double-resonant
1H/23Na-Coil, 5 patients with pathological LNs were
examined at 7 Tesla. Here, the first in vivo images of
human lymph nodes are demonstrated using simultaneous
1H/23Na-imaging where pathological LNs revealed a higher
relative sodium signal.
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