Comparing different contrasts for myelin-related cortical mapping at 7T

The current data show a comparison between different MRI contrasts at 7T that were used previously to map cortical myelin content. Previous papers showed that differences in intensity levels between the cortical areas may reflect the overall cortical myelin content. However, it is not clear whether different contrasts (i.e. weighted vs. quantitative) show comparable myelination patterns. Minor differences were found between the tested contrasts (T1w, T2*w, R1, qT2*, T1w/T2w, R1/qT2*). These variances could be partially induced by qT2* effects. Nevertheless, other factors like curvature and cortical thickness should be taken into consideration for future analyses.

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