Meeting Banner
Abstract #3241

Biexponential T 1 Relaxation at 7T: Characterization and Impact on T 1 Mapping

James A. Rioux 1 , Ives R. Levesque 1,2 , and Brian K. Rutt 1

1 Radiology, Stanford University, Stanford, CA, United States, 2 Medical Physics Unit, and Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada

White matter exhibits biexponential relaxation, which is neglected in T 1 measurements at low field strengths, but which is a significant source of variation between reported T 1 values at high field. If the effect of the shorter T 1 component can be removed, such that only the longer component is measured, the resulting T 1 value will be more reproducible across sites and protocols. We characterized biexponential relaxation in white matter at 7T, finding T 1 values of 1349ms and 57ms, with 11% of signal from the short component. Based on these values we recommend using minimum inversion times of 150-200ms in inversion-recovery-based sequences.

This abstract and the presentation materials are available to members only; a login is required.

Join Here