Meeting Banner
Abstract #3270

Comparison of concentration-dependent signal intensities of MRI contrast media solutions obtained at different pulse sequences at 3T and 7T

Thomas Frenzel 1 , Pavol Szomolanyi 2 , Iris Noebauer-Huhmann 2 , Martin Rohrer 1 , Gregor Jost 1 , and Siegfried Trattnig 2

1 Bayer Healthcare, Berlin, Germany, 2 High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna / Vienna General Hospital, Vienna, Austria

The concentration dependent change of the signal intensity (SI) of commercially available contrast media (CM) were investigated in-vitro in human plasma at 37C at 3T and 7T, using spin- and gradient echo sequences. A nearly linear correlation between Gd-concentration and SI was observed only for very low concentrations (<1-3mM). At higher concentrations stable, increasing or decreasing SIs were observed. The dominant parameters influencing the SI were the pulse sequence, the field strength, the protein binding of the CA as well as their relaxivities, and their in-vivo concentrations. These results should be considered for (semi-) quantitative image evaluation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here