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Abstract #3287

Electrical Conductivity Images of Brain Metabolites using MR-based Tissue Property Mapping

Saurav ZK Sajib 1 , Ji Eun Kim 1 , Woo Chul Jeong 1 , Hyung Joong Kim 1 , Oh In Kwon 2 , and Eung Je Woo 1

1 Kyung Hee University, Yongin, Gyeonggi, Korea, 2 Konkuk University, Seoul, Korea

Electrical tissue conductivity is primarily determined by concentration and mobility of ions. If electrical current is carried by dissolved ions, the more ions generate more currents. In addition, the mobility of ions is restricted by heterogeneous membrane, current density of tissue dependent on the physical environment even though it has uniform ion concentration. Using MREIT technique, we provide electrical conductivity-based metabolite mapping with highly sensitive to its concentration changes. Together with in vitro measurement of metabolites by concentration changes, we performed phantom imaging to evaluate the proposed method showing a significant relationship between concentration and electrical conductivity of brain metabolites.

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