Abstract #3303
Total Variance Constrained Electrical Properties Tomography Using a 16-channel Transceiver Array Coil at 7T
Yicun Wang 1 , Xiaotong Zhang 1 , Jiaen Liu 1 , Pierre-Francois Van de Moortele 2 , and Bin He 1,3
1
Department of Biomedical Engineering,
University of Minnesota, Minneapolis, Minnesota, United
States,
2
Center
for Magnetic Resonance Research, University of
Minnesota, Minneapolis, Minnesota, United States,
3
Institute
for Engineering in Medicine, University of Minnesota,
Minneapolis, Minnesota, United States
Electrical Properties Tomography (EPT) is able to
provide quantitative maps of electrical properties (EP)
using MRI, which holds promise in early cancer
diagnosis. Currently, the Helmholtz Equation-based EPT
approaches ignore gradient information on the tissue
boundary, causing severe EP reconstruction artifacts;
other studies require either a priori boundary
conditions that are subject to error, or dielectrical
padding that may cause difficulties in practical
settings. In this study, we proposed a total variance
promoting gradient-based algorithm that does not bear
the aforementioned limitations. Simulation and phantom
experiment at 7T have demonstrated feasibility of this
new approach.
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