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Abstract #3306

Investigating breast tumor malignancy with electric conductivity measurement

Ulrich Katscher 1 , Hiroyuki Abe 2 , Marko K Ivancevic 3 , and Jochen Keupp 1

1 Philips Research Europe, Hamburg, Germany, 2 Medical Center, University of Chicago, Chicago, Illinois, United States, 3 Philips Healthcare, Best, Netherlands

According to ex vivo studies, breast tumors exhibit a significantly altered conductivity, which opens the chance to increase MRI specificity of breast tumor characterization. Conductivity can be measured in vivo using Electric Properties Tomography (EPT). With EPT, a trend towards a correlation between conductivity and malignancy was indicated in initial breast tumor studies, however, without statistical significance. This study tests a statistically significant correlation between conductivity and malignancy. Lesion volume derived from pre/post contrast subtraction images was used as a priori information to stabilize EPT reconstruction. According to the results obtained, EPT is able for tumor malignancy staging.

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