Abstract #3306
Investigating breast tumor malignancy with electric conductivity measurement
Ulrich Katscher 1 , Hiroyuki Abe 2 , Marko K Ivancevic 3 , and Jochen Keupp 1
1
Philips Research Europe, Hamburg, Germany,
2
Medical
Center, University of Chicago, Chicago, Illinois, United
States,
3
Philips
Healthcare, Best, Netherlands
According to ex vivo studies, breast tumors exhibit a
significantly altered conductivity, which opens the
chance to increase MRI specificity of breast tumor
characterization. Conductivity can be measured in vivo
using Electric Properties Tomography (EPT). With EPT,
a trend towards a correlation between conductivity and
malignancy was indicated in initial breast tumor
studies, however, without statistical significance. This
study tests a statistically significant correlation
between conductivity and malignancy. Lesion volume
derived from pre/post contrast subtraction images was
used as a priori information to stabilize EPT
reconstruction. According to the results obtained, EPT
is able for tumor malignancy staging.
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