The impact of background removal techniques on the quantification of magnetic susceptibility in the human cortex

Quantitative susceptibility mapping (QSM) is sensitive to iron and myelin but pre-processing need to be performed in order to retrieve the QSM maps. The background removal step was analyzed and the performance and quality of some of the state of art background removal techniques in the estimated susceptibility of the brain cortex was compared in this study for the first time. While all methods have the expected high susceptibility values of primary sensory areas in the layer close to the white matter, the main differences lay in the outer layer of the brain cortex.

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