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Abstract #3318

Streaking Artifacts Reduction for QSM

Hongjiang Wei 1 , Wei Li 2 , Nian Wang 1 , and Chunlei Liu 1,3

1 Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, 2 University of Texas Health Science Center at San Antonio, TX, United States, 3 Depatment of Radoilogy, School of Medicine, Duke University, Durham, NC, United States

Quantifying susceptibility from the phase image is hampered by the ill-posed dipole filter inversion problem. The imperfect inversion on and near the conical surface results in streaking artifacts in the computed susceptibility maps. In this study, we introduced a novel image-space weighting function to suppress errors induced by imperfect phase measurement and unwrapping. This weighting function is applied in a joint L1 and L2 norm minimization procedure which can be solved rapidly using SPARSA solver. A significantly lower level of streaking artifacts is observed in the resulting susceptibility maps. The results are comparable to those obtained from COSMOS method, and the computation time for the reconstruction is less than one minute for a matrix size of 320320204

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