In Vivo Measurement of Free Creatine and Phosphocreatine Kinetics In Lower Leg Muscle.
Olusegun Adegbite 1 , Prodromos Parasoglou 1 , Lee Jae Seung 1 , Ding Xia 1 , and Ravinder R. Regatte 1
Radiology, NYU, Langone Medical Centre, New
York, New York, United States
The interconversion between PCr and Cr concentrations
under high energy demand is a major activity controlled
by creatine kinase (CK) reaction. In this study, we
measured the recovery of both PCr and Cr with high
temporal resolution through CEST and 31P-MRI, and the
preliminary results were presented.
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