In Vivo Measurement of Free Creatine and Phosphocreatine Kinetics In Lower Leg Muscle.

The interconversion between PCr and Cr concentrations under high energy demand is a major activity controlled by creatine kinase (CK) reaction. In this study, we measured the recovery of both PCr and Cr with high temporal resolution through CEST and 31P-MRI, and the preliminary results were presented.

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