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Abstract #3387

Multiple Preparation Magnetic Resonance Fingerprinting (MP-MRF): An Extended MRF Method for Multi-Parametric Quantification

Christian Anderson 1 , Ying Gao 1 , Chris Flask 1,2 , and Lan Lu 2,3

1 Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States, 2 Radiology, Case Western Reserve University, Cleveland, Ohio, United States, 3 Urology, Case Western Reserve University, Cleveland, Ohio, United States

Magnetic resonance fingerprinting (MRF) offers rapid simultaneous multi-parametric quantification, and also provides the potential to generate maps of other parameters. We have developed a novel scheme named "Multi-Preparation MRF" (MP-MRF) that implements adaptable magnetization preparations periodically during the dynamic MRF acquisition. Our initial simulations of the MP-MRF methodology show sensitivity to diffusion and perfusion contrast and reasonable estimates of T1, T2, and velocity in Shepp-Logan phantoms.

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