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Abstract #3484

ExTracT: extracting tract terminations using diffusion imaging

Claude J. Bajada 1 , Hamied A. Haroon 2 , Hojjatollah Azadbakht 2 , Geoff J. M. Parker 2 , Matthew A. Lambon Ralph 1 , and Lauren L. Cloutman 1

1 Neuroscience and Aphasia Research Unit, School of Psychological Sciences, The University of Manchester, Manchester, United Kingdom, 2 Centre for Imaging Science, Institute of Population Health, The University of Manchester, Manchester, United Kingdom

Diffusion tractography is the only method available to study the brains white matter anatomy in-vivo, however, it does not provide accurate information about the terminations of white matter tracts. This poster presents a method to extract white matter tract terminations (ExTracT) using tractography, and illustrates the method by performing the technique on the temporal lobe. The results demonstrate that ExTracT is capable of reliably identifying voxels near the brains surface that contribute to a tract, enabling the generation of tract termination maps. These termination maps can be used to improve basic white matter anatomical knowledge in health and disease.

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