Abstract #3486
Diffusion Tensor Tractography of Human Spinocerebellar, Cortico-Ponto-Cerebellar and Dentate-Rubro-Thalamo-Cortical Pathways
Khader M Hasan 1 , Zafer Keser 2 , Arash Kamali 3 , Nuray Yozbatiran 2 , and Gerard E Francisco 2
1
Diagnostic and Interventional Imaging,
University of Texas Health Science Center, Houston,
Texas, United States,
2
Physical
Medicine and Rehabilitation, University of Texas Health
Science Center and TIRR NeuroRecovery Research Center,
Houston, Texas, United States,
3
Department
of Diagnostic Radiology, Division of Neuroradiology,
Johns Hopkins University, Maryland, United States
In this study, we demonstrate the feasibility of in vivo
delineation and 3D reconstruction of the main cerebellar
pathways using high resolution diffusion tensor imaging
(DTI) data on 3.0 T in a systematic way. We also
identified and quantified bilaterally each tract volume
and its corresponding DTI scalar metrics. Although these
tracts have been described previously, a clear
deterministic tractography protocol to reconstruct all
these tracts and their corresponding DTI attributes has
not been reported.We believe that revealing the
connections of cerebellum with extracerebellar
structures is a crucial step in understanding
underestimated roles of cerebellum.
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