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Abstract #3588

Non-enhanced Hybrid Arterial Spin Labeling MRA for assessment of the cervical carotid and vertebral arteries in patients with suspected/ known cerebral ischemia: preliminary clinical experience

Dinesh Gooneratne 1 , Yuliya Perchyonok 1,2 , Greg Fitt 1 , Andrew Kemp 3 , Tim Spelman 4 , Shivraman Giri 5 , Davide Piccini 6 , Robert R Edelman 7 , Marion Simpson 8 , Helen Dewey 8,9 , Geraldine Ng 8 , Ioannis Koktzoglou 7 , and Ruth P Lim 1,2

1 Radiology department, Austin Hospital, Melbourne, Victoria, Australia, 2 Melbourne University, Victoria, Australia, 3 Austin Hospital, Victoria, Australia, 4 Burnet Institute, Victoria, Australia, 5 Siemens Healthcare USA, Pennsylvania, United States, 6 Advanced Clinical Imaging Technology, Siemens Healthcare IM BM PI, Lausanne, Switzerland, 7 NorthShore University HealthSystem, Illinois, United States, 8 Neurology Department, Austin Hospital, Victoria, Australia, 9 Neurology Department, Eastern Health, Victoria, Australia

A Non-enhanced Hybrid Arterial Spin Labeling MRA (NoHASL MRA) technique for assessment of the extracranial cervical arteries was evaluated. 15 patients with suspected cerebral ischemia underwent NoHASL followed by contrast enhanced MRA (CE-MRA). 18 arterial segments were assessed by 2 neuroradiologists for diagnostic confidence, internal carotid artery and vertebral artery stenosis against CE-MRA as the reference standard. There was no significant difference between dichotomized diagnostic and non-diagnostic confidence scores for the ICA, with moderate correlation between ICA bulb absolute diameters. NoHASL shows promise as a relatively rapid, non contrast sequence for assessment of cervical arterial disease.

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