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Abstract #3637

A simple BOLD contrast model based on functional activation pattern and k-space trajectory

Vimal Singh 1 and David Ress 2

1 Electrical Engineering, University of Texas at Austin, Austin, Texas, United States, 2 Neuroscience, Baylor College of Medicine, Hosuton, Texas, United States

This work presents a simple theory that accounts for the interaction of any k-space trajectory and echo time on BOLD contrast. The theory quantifies the need for different TEs to obtain best contrast for different acquisition trajectories. It also allows comparison of BOLD contrast available from different trajectories over various echo times. The theory was tested by performing high-resolution fMRI in superior colliculus using a variety of single- and dual-echo spiral trajectories and EPI as echo time was varied. . The proposed theory shows a satisfactory fit to the empirical data.

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