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Abstract #3642

Can high-resolution T1W 3-Dimensional (3D) gradient recalled echo (GRE) with 2-Point Dixon derived fat-water separation (FLEX) replace conventional T1W Turbo Spin-Echo (TSE) imaging for assessment of prostate cancer?

Karim B Samji 1,2 , Abdulmohsen Alrashed 1,2 , Wael M Shabana 1,2 , Matthew DF McInnes 1,2 , and Nicola Schieda 1,2

1 Department of Medical Imaging, The Ottawa Hospital, Ottawa, ON, Canada, 2 University of Ottawa, Ottawa, ON, Canada

T1W TSE imaging is fundamental for prostate cancer staging with MRI. This study compared a modified high-resolution free breathing 2-Point Dixon GRE sequence with fat-water separation (FLEX-LAVA) to T1W TSE as a potential time saving measure. There was no difference in detection of nodal or skeletal metastases and image quality was comparable or slightly improved with FLEX-LAVA. Our results suggest that T1W TSE can be safely replaced in prostate cancer MRI examinations using a high resolution 2-Point Dixon GRE sequence therefore decreasing examination time.

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