Abstract #3644
Hepatic Fat Quantification for suspected NAFLD Patients Using 3 Different Methods: HISTO, 3D Multi-Echo GRE DIXON and Invasive Liver Biopsy
Wei Wang 1 , Xiuzhong Yao 1 , Hongmei Yan 2 , Hua Bian 2 , Xiaodong Zhong 3 , Radhouene Neji 4 , Caixia Fu 5 , Hui Liu 6 , Dehe Weng 5 , Ignacio Vallines 6 , and Mengsu Zeng 1
1
Radiology Department, Zhongshan Hospital,
Fudan University, Shanghai, Shanghai, China,
2
Endocrinology
Department, Zhongshan Hospital, Fudan University,
Shanghai, China,
3
MR
collaborations, Siemens Healthcare, Atlanta, Georgia,
United States,
4
MR
collaborations, Siemens Healthcare, Frimley, Camberley,
United Kingdom,
5
Application
Department, Siemens Shenzhen Magnetic Resonance Ltd.,
Shenzhen, Guangdong, China,
6
MR
collaborations, Siemens Healthcare, Shanghai, China
Accurate non-invasive detection and quantification of
proton density fat fraction (PDFF) as a marker for liver
fat in patients with non-alcoholic fatty liver disease
(NAFLD) is gaining increasing interest. The aim of this
study was to evaluate both rapid single breath-hold,
multi-echo, T2 corrected single-voxel spectroscopy(
HISTO ), and a recently developed, multi-echo 3D
gradient echo acquisitions using a hybrid multi-step
fitting approach (Advanced Dixon, AD) with conventional,
invasive liver biopsy as a reference for hepatic fat
quantification in NAFLD patients.
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