Abstract #3650
Dixon Fat Suppression for Off-resonant Water Imaging of Superparamagnetic Iron Oxide Nanoparticles
Dirk Krger 1 , Silvia Lorrio Gonzlez 1 , and Ren M. Botnar 1
1
Division of Imaging Sciences & Biomedical
Engineering, King's College London, London, United
Kingdom
The aim of this project is to improve and validate a fat
saturation technique for MR imaging with magnetic
nanoparticles (MNPs). Inversion Recovery with
ON-resonant water suppression (IRON) has been shown to
produce reliable positive contrast images with MNPs. The
most common fat saturation technique in combination with
IRON is a spectrally selective pre-saturation pulse
(SPIR). We used a two echo Dixon method instead of SPIR
to achieve fat saturation in a phantom study. The Dixon
method demonstrated superior fat suppression ability
compared to SPIR while achieving the same positive
contrast of MNP rich areas of the phantom.
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