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Abstract #3662

Self-Navigated 3D Whole Heart Coronary MRI with VARPRO Fat-Water Separation

Davide Piccini 1,2 , Peter Kellman 3 , Diego Hernando 4 , Simone Coppo 2 , Gabriele Bonanno 2 , and Matthias Stuber 2

1 Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 2 Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL) / Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 3 Laboratory of Cardiac Energetics, National Institutes of Health/NHLBI, Bethesda, Maryland, United States, 4 Department of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, United States

Respiratory self-navigation (SN), using a modified 3D radial trajectory has successfully been tested for whole-heart coronary MRA achieving 100% scan efficiency. However, radial imaging in combination with standard CHEmical Shift Selective (CHESS) pulses exhibits a compromised fat-suppression performance due to fat magnetization recovery during the acquisition. A multi-echo version of SN 3D radial MRA was combined with the VARiable PROjection method (SN-VARPRO) for Dixon-like fat-water separation with flexible echo-times and compared to the SN-CHESS acquisition in volunteers. Increased fat suppression was achieved with SN-VARPRO. A trend for increased vessel sharpness and similar visualized length was obtained with respect to SN-CHESS.

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