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Abstract #3688

A fast and novel groupwise-non-rigid registration methodology for freezing motion in DCE-MRI

KS Shriram 1 , Dattesh D Shanbhag 2 , Sheshadri Thiruvenkadam 2 , Venkata Veerendranadh Chebrolu 2 , Sandeep N Gupta 3 , and Rakesh Mullick 4

1 Biomedical Signal Analysis Laboratory, GE Global Research, Bangalore, Karnataka, India, 2 Medical Image Analysis Laboratory, GE Global Research, Bangalore, Karnataka, India, 3 Clinical Systems & Signal Processing, GE Global Research, Niskayuna, NY, United States, 4 Diagnostics & Biomedical Technologies, GE Global Research, Bangalore, Karnataka, India

We have introduced a fast group-wise registration scheme for correction of non-rigid motion in prostate DCE exams. We demonstrate the robustness of the algorithm in correcting motion even in presence of coil shine through artifacts, and retaining signal characteristics. Overall, motion correction results in lower dispersion of pK parameters in a given tissue ROI and improved confidence in interpretation of DCE data.

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