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Abstract #3694

Simultaneous quantification of intravascular blood T 1 and T 2 with multiple-readout TRUST (mTRUST)

Zachary B Rodgers 1 and Felix W Wehrli 1

1 Radiology, University of Pennsylvania, Philadelphia, PA, United States

Simultaneous measurement of intravascular blood T 1 and T 2 is a promising approach for fast, accurate quantification of whole-brain venous oxygen saturation (Y v ), as the T 1 values can be used to determine hematocrit, which is needed to convert measured T 2 to Y v . We describe a modification of the recently developed TRUST T 2 -quantification method, with addition of multiple EPI readouts (mTRUST) to allow concurrent measurement of T 1 . mTRUST was applied in four subjects, demonstrating good precision for T 1 and T 2 estimation. T 1 values were slightly lower than recent literature, potentially due to incomplete inversion of blood present in the later EPI readouts.

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