Quantitative 19 F MR Molecular Imaging with B 1 -Mapping Compensation

This study presents a strategy to more accurately quantify the sparse ¹⁹ F signal from ₃ integrin targeted perfluorocarbon nanoparticle emulsions with a ¹ H image-based actual flip angle B ₁ -mapping correction to the ¹⁹ F and ¹ H images, acquired with a simultaneous dual-frequency ultra-short echo time balanced steady state free precession sequence, in a phantom and an in vivo setting using a VX2 tumor model implanted into rabbits.

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