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Abstract #3731

Spatio-temporal Artifact Correction of Multi-dimensional Spectroscopic Imaging Data

Brian Burns 1 , Neil Wilson 2 , and M. Albert Thomas 2,3

1 Department of Bioengineering, UCLA, Los Angeles, CA, United States, 2 Medical Physics, IDP, UCLA, Los Angeles, CA, United States, 3 Department of Radiology, UCLA, Los Angeles, CA, United States

Current phase correction techniques in multi-dimensional spectroscopic imaging (MRSI) do not take into account the spatio-temporal nature of phase errors because they were designed for single voxel methods. This work categorizes phase errors in 4D MRSI (2D spatial+2D spectral) as time, space, or space and time varying, and proposes a post-processing pipeline that decouples these errors so they are removed in the appropriate domain. The Interleaved Navigator Scan corrected Echo-Planar J-Resolved Spectroscopic Imaging (INSEP-JRESI) sequence is proposed. Results from gray matter phantom scans using this new sequence and pipeline demonstrate the viability of this technique compared to MRSI-adapted Klose's methods.

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