Abstract #3731
Spatio-temporal Artifact Correction of Multi-dimensional Spectroscopic Imaging Data
Brian Burns 1 , Neil Wilson 2 , and M. Albert Thomas 2,3
1
Department of Bioengineering, UCLA, Los
Angeles, CA, United States,
2
Medical
Physics, IDP, UCLA, Los Angeles, CA, United States,
3
Department
of Radiology, UCLA, Los Angeles, CA, United States
Current phase correction techniques in multi-dimensional
spectroscopic imaging (MRSI) do not take into account
the spatio-temporal nature of phase errors because they
were designed for single voxel methods. This work
categorizes phase errors in 4D MRSI (2D spatial+2D
spectral) as time, space, or space and time varying, and
proposes a post-processing pipeline that decouples these
errors so they are removed in the appropriate domain.
The Interleaved Navigator Scan corrected Echo-Planar
J-Resolved Spectroscopic Imaging (INSEP-JRESI) sequence
is proposed. Results from gray matter phantom scans
using this new sequence and pipeline demonstrate the
viability of this technique compared to MRSI-adapted
Klose's methods.
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