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Abstract #3764

Highly dynamic k T -points to minimize the B 1 + inhomogeneity effects in T 2 -weighted imaging at 7T

Florent Eggenschwiler 1 , Kieran R. O'Brien 2 , Daniel Gallichan 1 , Rolf Gruetter 1,2 , and Jose P. Marques 3

1 Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland, 2 Department of Radiology, University of Geneva, Geneva, Geneva, Switzerland, 3 Department of Radiology, University of Lausanne, Lausanne, Vaud, Switzerland

At ultra-high magnetic field, the inhomogeneous distribution of the B 1 + field can significantly impair the quality of turbo spin echo sequences. Static k T -points where a unique pulse is designed in the STA regime and then dynamic k T -points where a specific k T -point pulse is optimized for each pulse of the turbo spin echo sequence were proposed to generate T 2 -weighted images with increasingly improved signal and contrast homogeneities. In this work, the dynamic k T -point design is further improved by allowing an increased flexibility for the optimization of the excitation pulse and by choosing carefully the cost function used in the optimization algorithm.

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