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Abstract #3772

Single echo EPI sequence with dynamic distortion correction: minimization of errors due to motion and breathing.

Barbara Dymerska 1 , Benedikt Poser 2 , Wolfgang Bogner 1 , Eelke Visser 3 , Korbinian Eckstein 1 , Pedro Cardoso 1 , Roland Beisteiner 1,4 , Markus Barth 5 , Siegfried Trattnig 1 , and Simon Daniel Robinson 1

1 High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Vienna, Austria, 2 Department of Psychology and Neuroscience, Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 3 FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 4 Department of Neurology, Medical University of Vienna, Vienna, Austria, 5 Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia

The geometric distortions encountered in EPI can be corrected using static or dynamic distortion correction methods. The static approach does not account for temporal B0 changes caused by breathing and motion over the course of an fMRI experiment. Here, we propose a single-echo EPI sequence in which the echo time is jittered between two values. Field maps are calculated between adjacent volumes, enabling a reference-free dynamic distortion correction. We show that this method generates accurate maps of local deviations from the static magnetic field even in the presence of large motion (up to 12) and fast breathing (0.36 Hz) without compromising BOLD sensitivity or spatiotemporal resolution.

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