Artifact Associated with Fat Suppression in Spin-Echo EPI

This study investigated a fat-related artifact that occurs when spectral-fat saturation is used with spin-echo EPI. This artifact was detected in humans and phantoms for a variety of imaging parameter settings, was significant compared to task associated signal changes, diminished with longer TR as well as fewer slices, and exhibited a power spectrum with a single broad peak at 0.133/TR Hz. This finding is relevant for all spin-echo EPI experiments, including fMRI and DTI. While further investigation is required to understand the mechanisms causing this artifact, water excitation is recommended for acquiring fat-free images with spin-echo EPI.

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