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Abstract #3805

Accelerated Breath-hold Liver Imaging Using Additional Information from Free-breathing Acquisitions

Feiyu Chen 1,2 , Feng Huang 3 , Dan Zhu 1 , Jia Ning 1 , and Huijun Chen 1

1 Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing, China, 2 Electrical Engineering, Stanford University, Stanford, California, United States, 3 Philips Healthcare (Suzhou). Co. Ltd, Jiangsu, China

Dynamic contrast-enhanced MR imaging is a promising technique for treating various hepatic diseases. Breath-hold 3D Gradient echo sequence is currently used for achieving multi-phase volumetric images of the liver. However, conventional 3D whole-liver imaging requires a breath-hold duration of more than 30 seconds. 2D-CAIPIRINHA, which accelerates the acquisition through controlled-aliased under-sampling, has been applied to reducing breath-hold duration to eight seconds at a reduction factor of four. However, down-sampling of k-spaces leads to aliasing artifacts in reconstructed images. In this research, we propose a new method combining temporal-shifted 2D-CAIPIRINHA sequence with PEAK-GRAPPA reconstruction. This approach further utilizes additional information acquired from the free-breathing periods before and after the breath-holding, which were wasted in traditional acquisition, to reduce the aliasing artifacts.

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