Accelerated Breath-hold Liver Imaging Using Additional Information from Free-breathing Acquisitions
Feiyu Chen 1,2 , Feng Huang 3 , Dan Zhu 1 , Jia Ning 1 , and Huijun Chen 1
Center for Biomedical Imaging Research,
School of Medicine, Tsinghua University, Beijing, China,
Engineering, Stanford University, Stanford, California,
Healthcare (Suzhou). Co. Ltd, Jiangsu, China
Dynamic contrast-enhanced MR imaging is a promising
technique for treating various hepatic diseases.
Breath-hold 3D Gradient echo sequence is currently used
for achieving multi-phase volumetric images of the
liver. However, conventional 3D whole-liver imaging
requires a breath-hold duration of more than 30 seconds.
2D-CAIPIRINHA, which accelerates the acquisition through
controlled-aliased under-sampling, has been applied to
reducing breath-hold duration to eight seconds at a
reduction factor of four. However, down-sampling of
k-spaces leads to aliasing artifacts in reconstructed
images. In this research, we propose a new method
combining temporal-shifted 2D-CAIPIRINHA sequence with
PEAK-GRAPPA reconstruction. This approach further
utilizes additional information acquired from the
free-breathing periods before and after the
breath-holding, which were wasted in traditional
acquisition, to reduce the aliasing artifacts.
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