Abstract #3931
Change of Venous Susceptibility upon Visual Activation: 3D Multi-echo GRE vs. GRE-EPI Functional QSM
PINAR SENAY ZBAY 1,2 , Cristina Rossi 1 , Geoffrey Warnock 3 , Felix Kuhn 3 , Klaas Paul Prssmann 2 , and Daniel Nanz 1
1
Department of Radiology, University Hospital
Zrich, Zrich, Switzerland,
2
Institute
of Biomedical Engineering, ETH Zrich, Zrich,
Switzerland,
3
Department
of Nuclear Medicine, University Hospital Zrich, Zrich,
Switzerland
This study compared BOLD- and QSM-based neuronal
activation patterns and changes of venous magnetic
susceptibility under visual-stimulation as observed in
data acquired with (i) traditional repeated fast
whole-brain covering 2D GRE-EPI scans versus with (ii)
single 3D-GRE scans. T-score-maps from statistical
parametric mapping of the EPI-acquired fQSM
time-series-data and difference maps (ON-OFF) for both
EPI-fQSM and 3D-GRE-fQSM are presented. Image quality of
3D-GRE-fQSM and its difference-map were superior to
corresponding EPI-QSM data. 3D-GRE-fQSM detected larger
reduction of venous magnetic susceptibility upon visual
stimulation than EPI-fQSM. 3D-GRE-fQSM might have a
potential for studies with a focus on the venous vessel
tree.
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