Abstract #3978
Three-dimensional oxygen-enhanced human lung MRI using ultra-fast balanced Steady-State Free Precession
Orso Pusterla 1 , Grzegorz Bauman 1 , Gregor Sommer 2 , Christoph Jud 3 , Philippe C. Cattin 3 , and Oliver Bieri 1
1
Radiological Physics, Department of
Radiology, University of Basel Hospital, Basel,
Switzerland,
2
Clinic
of Radiology and Nuclear Medicine, Department of
Radiology, University of Basel Hospital, Basel,
Switzerland,
3
Medical
Image Analysis Center (MIAC), University of Basel
Hospital, Basel, Switzerland
Ultra-fast balanced Steady-State Free Procession
(ufSSFP) pulse sequence was proposed for morphological
and functional lung imaging, offering short acquisition
times with exceptional SNR and CNR. In this work, it was
demonstrated the feasibility of three-dimensional
oxygen-enhanced (OE) lung MRI with ufSSFP in healthy
volunteers taking into account a possible bias in OE
contrast images due to volume-dependent signal intensity
modulations. The proposed technique has the potential to
be used for subjects with lung diseases.
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