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Abstract #3978

Three-dimensional oxygen-enhanced human lung MRI using ultra-fast balanced Steady-State Free Precession

Orso Pusterla 1 , Grzegorz Bauman 1 , Gregor Sommer 2 , Christoph Jud 3 , Philippe C. Cattin 3 , and Oliver Bieri 1

1 Radiological Physics, Department of Radiology, University of Basel Hospital, Basel, Switzerland, 2 Clinic of Radiology and Nuclear Medicine, Department of Radiology, University of Basel Hospital, Basel, Switzerland, 3 Medical Image Analysis Center (MIAC), University of Basel Hospital, Basel, Switzerland

Ultra-fast balanced Steady-State Free Procession (ufSSFP) pulse sequence was proposed for morphological and functional lung imaging, offering short acquisition times with exceptional SNR and CNR. In this work, it was demonstrated the feasibility of three-dimensional oxygen-enhanced (OE) lung MRI with ufSSFP in healthy volunteers taking into account a possible bias in OE contrast images due to volume-dependent signal intensity modulations. The proposed technique has the potential to be used for subjects with lung diseases.

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