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Abstract #4057

Feasibility of Temperature Imaging of Knee Joint Cartilage under Thermal Therapy using Water Proton Resonance Frequency Shift

Atsushi Shiina 1 , Kenji Takahashi 2 , Jiro Nakano 3 , and Kagayaki Kuroda 1

1 Graduate School of Engineering, Tokai University, Hiratsuka, Kanagawa, Japan, 2 Department of Orthopaedic Surgery, Nippon Medical School, Bunkyo, Tokyo, Japan, 3 School of Information Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan

Feasibility of MR temperature imaging for joint cartilage using conventional water proton resonance frequency technique was demonstrated. Laser heating experiments with cartilage samples in vitro excised from porcine knee joints showed clear temperature elevation images of the thin cartilage region of 1-2 mm thickness. The temperature coefficient of the water proton resonance frequency was -0.0108 ppm/degree C. These results may be a first step to apply the noninvasive temperature imaging technique for thermally induced pain-relief for a patient with osteoarthritis.

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