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Abstract #4100

Qualitative and quantitative assessment of intrahepatic cholangiocarcinoma using diffusion weighted imaging with histopathologic correlation: preliminary results from a bi-center series.

Sara C Lewis 1 , Shingo Kihira 1 , Cecilia Besa 2 , Hongfa Zhu 3 , Swan Thung 3 , Kartik Jhaveri 4 , and Bachir Taouli 5

1 Radiology, Mount Sinai Medical Center, New York, NY, United States, 2 Translational and Molecular Imaging Institute, Mount Sinai Medical Center, New York, NY, United States, 3 Pathology, Mount Sinai Medical Center, New York, NY, United States, 4 Radiology, University Health Network Mt. Sinai and Womens' College Hospital, Toronto, Ontario, Canada, 5 Radiology, Translational and Molecular Imaging Institute, Mount Sinai Medical Center, New York, NY, United States

This study evaluates qualitative and quantitative SS EPI diffusion-weighted imaging for assessment of intrahepatic cholangiocarcinoma. Initial results demonstrate high lesion conspicuity with approximately a third of lesions showing a target appearance. ADC of grade 3 tumors was lower than those of grade 2 without reaching significance. These preliminary results suggest that DWI is useful for cholangiocarcinoma detection, however ADC quantification for assessing tumor grade needs further validation.

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