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Abstract #4110

Respiratory motion-resolved compressed sensing reconstruction of free-breathing radial acquisition for improved dynamic liver MRI with hepatobiliary contrast agent

Hersh Chandarana 1,2 , Li Feng 1,2 , Justin Ream 1 , Annie Wang 1 , James Babb 1 , Kai Tobias Block 1,2 , Mary Bruno 1 , Daniel K Sodickson 1,2 , and Ricardo Otazo 1,2

1 Radiology, Center for Biomedical Imaging, NYU School of Medicine, New York, NY, United States, 2 Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), NYU School of Medicine, New York, NY, United States

This work applies the novel XD-GRASP technique for continuous free-breathing motion-sorted golden-angle radial MRI to the examination of patients undergoing liver MRI using the hepatobiliary contrast agent Gd-EOB-DTPA, which is known to result in suboptimal quality of the arterial phase. Continuously acquired k-space data were sorted into contrast-enhancement and respiratory phases, and reconstructed using a compressed sensing approach that exploits sparsity along the dynamic dimensions. Our results demonstrate that arterial-phase XD-GRASP reconstructions had superior image quality compared to conventional GRASP, as well as to standard breath-hold examinations. XD-GRASP has the potential to improve imaging in patients undergoing Gd-EOB-DTPA enhanced MRI.

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