Abstract #4136
Autocorrelation Analysis of Hepatic Fibrosis on MRI
Jonathan F. Brand 1 , Lars R. Furenlid 1,2 , Maria I Altbach 2 , Jean-Philippe Galons 2 , Tulshi Bhattacharyya 2 , Achuyt Bhattacharyya 3 , Ali Bilgin 2,4 , Zhitao Li 4 , and Diego R. Martin 2
1
College of Optical Sciences, University of
Arizona, Tucson, AZ, United States,
2
Department
of Medical Imaging, University of Arizona, Tucson, AZ,
United States,
3
Department
of Pathology, University of Arizona, Tucson, AZ, United
States,
4
Electrical
and Computer Engineering, University of Arizona, Tucson,
AZ, United States
The staging of hepatic fibrosis is critical to
monitoring chronic liver disease progression. The
current gold standard is liver biopsy which is invasive,
has associated risks, and results are affected by
sampling errors. The objective of this study is to use
high resolution MRI to detect the textural change in the
liver due to fibrosis and locally analyze the tissue
with a mathematical observer to grade fibrosis on a
scale consistent with the standard METAVIR score used in
biopsy.
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